QF - PCR

QF-PCR uses fluorescent labelled primers to amplify STR regions from DNA, by PCR. Short tandem repeats (STR) are highly polymorphic sequences found in the human DNA. The amount of fluorescently labelled amplicons are measured after fragment length separation in capillary electrophoresis. QF-PCR is a quantitative method that determines the presence of different alleles which means the determination of chromosomal copy number . Which leads to diagnosis of fetal chromosomal ploidy within a working day! (4-5 hours)

ChromoQuant® QF-PCR kits are a family of products for fast diagnosis of the most common chromosomal disorders in foetuses. ChromoQuant® detects Trisomy 21 (Down syndrome), Trisomy 13 (Patau syndrome), Trisomy 18 (Edwards syndrome) and aneuploidies in the sex chromosomes X and Y, i.e. Klinefelter syndrome and Turner syndrome.