EasyPGX® ready DPYD kat.č. RT026 (48 test, CE IVD)
Detection, by allelic discrimination, of the DPYD gene polymorphisms DPYD*2A (IVS14+1G>A, c.1905+1G>A), DPYD*13 (c.1679T>G), DPYD D949V (c.2846A>T) and DPYD IVS10 (c.1129–5923C>G), associated with the toxicity due to the treatment with Fluoropyrimidines. Each mix allows the co-amplification of the mutant sequence as well as the wild-type sequence.
DNA from whole blood.